MEDICATIONS

MEDICATIONS GROUPED BY CLASS
SPECIFIC TREATMENTS & DOSAGES

Emergency/Resuscitative:

            N.B.  For Klingon patients, double the listed doses to compensate for brak’lul physiology.

Inaprovaline, chloromydride – a commonly used class of cardiostimulatory drugs.  Indicated for treatment of cardiogenic and hypovolemic shock, i.e. myocardial infarction (“heart attack”), traumatic cardiac arrest, other causes of sudden cardiac failure.  For trauma cases, administer 10 milligrams bolus dose by hypospray; maintain on intravenous drip of 1 mg/hour.

Cordrazine, tricordrazine – powerful corticosteroid-based stimulants (similar biochemically to adrenaline).  In humanoid patients, these drugs increase heart rate, blood pressure and respiration rate; secondary effects such as nausea, muscle tremors and abnormal mentation are common.  Indicated for bradycardia (abnormally slow heart rate), cardiac arrest, hypovolemic shock, and anaphylactic reactions.  For resuscitation of the asystolic (pulseless) trauma patient, give 0.05 mg/kg (3.5 mg in the "average" 70-kg humanoid) cordrazine by IV every 5 minutes according to ACLS protocols.
            N.B.  Overdose (more than 0.1 mg/kg, or more than 7 mg for the “average” 70-kg humanoid) results in extremely high blood pressure, psychosis, tachycardia (abnormally high heart rate) and potentially death due to ventricular fibrillation or cerebrovascular accident (“stroke”).  25 mg in most humanoids is an instantly fatal overdose.
            N.B.  Cordrazine and tricordrazine are Schedule IV drugs; use with caution.

Cortolin, formazine – anticholinergic agents, used to treat bradycardia, also used in resuscitation.  In patients with pulseless electrical activity (PEA), give 1 mg bolus dose intravenously.  If using formazine, give 10 mg in divided doses, i.e. 2 mg every 5 minutes if the patient has cardiac activity, 5 mg every 10 minutes if in PEA or asystolic.

Delactovine, masiform-D, quadroline – class of systemic stimulants with vasopressor properties.  Use in combination with inaprovaline, et al. to prevent shock and cardiovascular collapse in trauma patients.  After cardiac function has been established, give 15 mg delactovine bolus dose, or any of these drugs in an IV drip of 0.3 mg/kg (approximately 20 mg total dose for the average 70-kg patient). Do not use quadroline in patients taking loop diuretics, as fatal arrhythmias can result.

Leporazine, morathial series – combination drugs that provide convenient, “one-shot” dosing for treatment of most cardiopulmonary sequelae of traumatic shock; the complete series provides cardiac stimulation, anti-arrhythmic protection, and respiratory support.  Give 15 mg bolus dose IV by hypospray, then 5 mg doses every 30 minutes thereafter.

Dexalin, pulmozine – commonly used emergency respiratory therapy drugs; these increase the circulatory system’s oxygen carrying capacity and may limit bronchospasm in anaphylactic shock.  Give 10 mg bolus dose IM by hypospray, or in an IV drip of 0.07 mg/kg/hour.  

Allergy and Respiratory:

Alizine – mast cell stabilizer, for use in most systemic allergic conditions.  Give 10 mg SC by hypospray once daily.

Cateline – histamine blocker and vasoconstrictor.  For anaphylactic shock secondary to allergic reaction, give 15 mg IV by hypospray in conjunction with 5 mg epinephrine SC.

Dexalin, pulmozine – see uses in “Emergency/Resuscitative” above.  For chronic obstructive pulmonary disorder, typical dosage is 50 mg PO in 2 divided doses daily, or in an IV drip of 0.1 mg/kg/hour in end-stage or terminal cases.

Tryptophan-lysine distillate – anti-inflammatory and immunostimulatory drug, used for mild to moderate respiratory infections; drowsiness and fatigue are the most common side effects.  Give up to 2 grams IM in four divided doses daily.  TLD is most effective when used in conjunction with the “PCS” regimen, that is, one bowl of hot chicken soup taken PO three times daily, with as much supportive care as possible.  

Analgesics:

Acinolyathin – non-steroidal anti-inflammatory drug (NSAID) for mild to moderate headache, muscle pain and joint pain.  Give 10 mg every four to six hours PRN for pain relief; increase dosing as needed, up to 40 mg. 
            N.B.  May be obtained OTC in up to 20 mg PO doses, not to exceed 80 mg/day without a prescription.

Hydrocortilene – long-duration corticosteroid analgesic and anti-inflammatory.  For joint injuries and mild to moderate osteoarthritis, inject 5 mg directly into the affected joint; repeat every 6 months as needed.

Morphenolog – synthetic opioid analgesic, for relief of severe chronic or acute pain; also controls seizures at low doses.  Begin treatment with a 5-mg/hour IV drip; taper to lowest dose that adequately controls the patient’s pain, up to 20 mg/hour.
            N.B.  Morphenolog is a Schedule II drug.  Use caution when prescribing, gradually wean the patient off the medication when discontinuing use, and watch carefully for signs of addiction.

Numinol tetramidaphin – antipyretic and anti-inflammatory drug.  For fever and muscle pain secondary to upper respiratory infection, give 250 mg PRN every 4 to 6 hours, not to exceed 1500 mg per 24 hours.

Terakine – COX-2 inhibitor for relief of moderate to severe headache, muscle pain and joint pain.  Give 50 mg PO three times daily.
            N.B.  Terakine is a Schedule V drug.

Tramadol – non-narcotic analgesic for relief of moderate chronic or acute pain.  Give 50 mg PO every four to six hours PRN; may increase dose up to 100 mg.
            N.B.  Tramadol is a Schedule III drug; use with caution and monitor for signs of abuse.

Triptocederine – combination synthetic opioid and NSAID, for moderate to severe acute or chronic pain.  Give 15 mg IM or 30 mg PO every 12 hours.
            N.B.  Triptocederine is a Schedule III drug; use with caution and monitor for signs of abuse.  

Anesthetics and Sedatives:

Anesthezine – inhaled sedative, typically used for riot control and other security applications.  In emergencies, it can also be used as a general surgical anesthetic; give 5 liters by nasal cannula with oxygen, at a 50% gas concentration.

Axonol - topical anesthetic.  For pain relief during minor surgical procedures (wound debridement, etc.), disinfect the skin site and spray axonol onto the skin.  For pain relief of minor injuries such as cuts, scrapes and burns, apply axonol cream liberally to the skin and cover with a sterile dressing.

Desflurane – inhaled halothane general anesthetic agent.  Give with oxygen or terrestrial air at a 5% gas concentration.  Desflurane and other halothane agents (enflurane, isoflurane, methoxyflurane and sevoflurane) are contraindicated in Bajoran, Vulcan and Romulan patients due to the high risk of malignant hyperthermia, a potentially fatal complication.

Kayolane – mild sedative, not commonly used due to common, undesirable side effects.  For general anxiety and stress conditions, give 5 mg PO or IM.
            N.B.  Kayolane is a Schedule IV drug; use with caution.

Melorazine – CNS depressant sedative.  For moderate to severe anxiety and stress, give 25 mg IM by hypospray.
            N.B.  Melorazine is a Schedule IV drug; use with caution.

Merfadon – sedative and muscle relaxant; drug of choice for pre-operative sedation.  Give 10 mg IV 30 minutes prior to surgery.

Pavulon – neural paralytic, used to induce neuromuscular blockade in rapid sequence intubation and in conjunction with general anesthesia during surgery.  Give 0.75 mg/kg (approximately 50 mg in the “average” 70-kg humanoid) as an initial dose, then 0.25 mg/kg (approximately 17 mg “average”) every 90 minutes as needed.
            N.B.  Patients must be mechanically ventilated while on this drug.

Quintethyl metasetamine – inhaled general anesthetic.  Give with oxygen or terrestrial air, at a 3% gas concentration. 

Antimicrobial (Antibiotic, Antiviral, Antifungal):

Corophizine – broad-spectrum antibiotic; Starfleet Medical directives suggest reserving use of this drug until other treatment modalities have failed, in order to reduce the possibility of developing drug-resistant microbes.  For septicemia or severe drug-resistant infection, give 10-15 mg/kg (700-1000 mg in the “average” patient) IM every 12 hours.

Genericillin - synthetic cillin-type antibiotic, effective against all Gram-negative and some Gram-positive aerobic organisms.  For treatment of susceptible bacterial infections, give 500-750 mg PO twice daily.  Do not use in patients with documented sensitivity to other cillins or cephalosporins.

Oseltamivir – antiviral drug used in the treatment of viral upper-respiratory infections.  For influenza, give 75 mg PO twice daily.  

Mycovir - anti-retroviral drug that inhibits viral binding via the CD4+ pathway.  For treatment of retroviral infection, give 150 mg PO four times daily, in combination with a reverse transcriptase inhibitor (nucleoside analog or non-nucleoside inhibitor depending on the causative organism), until viral load is confirmed undetectable for six weeks.

Phetetalin – macrolide antibiotic, effective against a wide range of bacterial infections, first-line treatment for most bacterial infective disorders.  Begin dosing at 50 mg PO or IM 3 times daily; dosage can be increased up to a total dose of 1 gram daily (500 mg in 2 doses, or 250 mg in four doses), although higher doses incur an unacceptably high risk of cardiac and renal damage.  Phetetalin may be used in patients with cillin or cephalosporin allergy.  Do not use in patients with documented sensitivity to other macrolide antibiotics.

Ryetalyn – antiviral medication, primarily effective against arboviruses.  Typically used as a specific for Rigelian fever, although other viral-mediated neurological fevers can be treated with this drug.  Typical dosage is 200 mg PO 4 times daily, or in an IV drip at 0.5 mg/kg/hour.  

Cardiac:

            N.B.  For Klingon patients, double the listed doses to compensate for brak’lul physiology.

Benjisidrine – Vulcan anti-arrhythmic medication.  To control premature ventricular contractions (PVC’s), give 25 mg IV as a loading dose and maintain on 15 mg PO or IV once daily.  Note that benjisidrine is relatively contraindicated in other species, although it may be used in Romulans and Bajorans without ill effects.

Cortolin – see uses in “Emergency/Resuscitative” above.  For treatment of bradycardia (abnormally slow heart rate) and some forms of atrioventricular block (first-degree and Type 1 second degree), give 250 mg IM or PO three times daily and gradually taper dose to the lowest level that suppresses the disease.

Delactovine, masiform-D, quadroline – see uses in “Emergency/Resuscitative” above.  For treatment of angina pectoris and supraventricular tachycardias, give 40 mg three times daily; increase dosing until arrhythmia is well controlled, up to 80 mg per dose. Do not use quadroline in patients taking furosemide or other loop diuretics.

Impedrezine – medication used to control high blood pressure in humanoid species.  For treatment of baseline hypertension, give 50 mg PO daily in 2 divided doses.

Metrazine – humanoid anti-arrhythmic medication.  For control of most tachycardic arrhythmias, give 100 mg IM or 200 mg PO every 8 hours. 

Miscellaneous:

Arithrazine - anti-radiation drug, most effective as a treatment for theta radiation poisoning.  For acute theta radiation exposure (>25 Gray), give 50 mg IV or IM four times daily.  If total radiation dose exceeds 100 Gray, arithrazine may be administered in an IV drip at 1 mg/Gray/hour.

Benzocyatizine – drug used to raise serum isoboramine levels in Trill patients.  For hypoisoboraminemia secondary to symbiont trauma, give 1.5 mg/kg (100 mg for an “average” 70-kg patient) IV every 12 hours, until isoboramine levels increase above 75 mcg/dL serum concentration.  Benzocyatizine is contraindicated for use in all other humanoid species.

Chlorhexidine - preoperative skin preparation agent and surgical scrub.  Scrub each hand for a minimum of 2 minutes, following proper aseptic technique, before any surgical procedure.

Dermaline gel – topical medication used to treat burn injuries.  To treat superficial (1^st-degree), partial-thickness (2^nd-degree) and full-thickness (3^rd-degree) burns, disinfect the burned area and surrounding skin, apply a thin layer of gel over the burned area, then cover with a loose sterile bandage.

Dermatiraelian plasticine - injectable collagenase compound used in plastic surgery.  To alter and maintain skin shape after a cosmetic procedure, inject up to 10 mg intradermally; wait 10 minutes to allow sufficient skin plasticity before attempting to alter skin shape.  Treatment should be repeated every 3 days or as needed to maintain desired results.

Furosemide - diuretic medication.  For edema, give 40 mg PO once daily; dosage may be increased as high as 200 mg daily.  Monitor patient's fluid intake and urine output while on this drug.  Use caution when combining furosemide or other loop diuretics with cardiac medications, as this class of medications can cause life-threatening cardiac arrhythmias.

Glucogen – concentrated hexose (blood sugars) solution.  For acute hypoglycemia in humanoid patients, give 50% solution in 1 liter of normal saline or Ringer’s lactate.

Glucophage – hypoglycemic drug used to lower abnormally high (greater than 200 mg/dL) blood sugar levels.  For acute diabetes mellitus, give 500 mg PO twice daily.

Hemolog – blood substitute for use in all oxygen-breathing humanoid species.  (Due to its mixture of iron, copper and magnesium-based globins, hemolog is pinkish-orange in color.)  For the hypovolemic trauma patient, give two 500-mL units IV, or as needed to replace lost blood volume.  Many species-specific forms of hemolog are available; these are preferable to the general-use form, and should be used if possible.  Do not use multi-species hemolog in Bolian patients, as the presence of Vulcan cuproglobins will cause a fatal agglutination reaction.

Hyronalin - multi-purpose anti-radiation drug used to treat most forms of radiation poisoning.  For acute radiation exposure (> 50 Gray), administer 500 mg IV once daily.  For prophylaxis of radiation exposure, administer 150 mg IV twice daily.  Hyronalin poisoning becomes evident at doses over 1000 mg bolus, or 7 days continuous use of the maximum daily dose.  Use caution when combining hyronalin with other anti-radiation drugs such as arithrazine.

Kelotane – drug used to accelerate healing in partial-thickness (2^nd-degree) and full-thickness (3^rd-degree) burns.  For every 1% of body surface area burned, give 10 mg SC by hypospray.

Lectrazine - drug used to stabilize renal function.  For acute renal failure (creatinine >2 mg/dL, BUN >20 mg/dL), give 25 mg IM or IV once daily, along with furosemide or another loop diuretic.

Polynutrient solution – total parenteral nutrition (TPN) given to malnourished patients.  Give 1 liter in an IV drip every 6 hours.

Tesokine - pediatric anabolic stimulant, predominantly used to treat cases of malnourishment secondary to inadequate gastrointestinal development in premature infants.  For Bajoran, Romulan and Vulcan neonates with symptoms of gastric insufficiency, give 0.5 mg/kg IV bolus every six hours along with polynutrient solution.  Tesokine is relatively contraindicated for use in all other species, as similar drugs exist with a better species-specific side effect profile.

Trianaline - drug used to treat percussive injuries (concussions, contusions, et al.)  Give 0.4 mg/kg (30 mg in the "average" 70-kg humanoid) IM or IV.  If symptoms persist, an additional 10-mg dose can be given, not to exceed 50 mg in 48 hours.  

Ophthalmic:

Busulfatine - ointment used for treatment of ocular flash burns, i.e. secondary to phaser or radiation exposure.  Apply a 1 cm ribbon of ointment in the affected eye twice daily.

Dorzolamide – drug used to treat ocular hypertension (abnormally high intra-ocular pressure, a precursor condition for glaucoma).  Give 1 drop in each eye twice daily; increase dosing until IOP can be maintained at a normal level.  Dorzolamide can also be used as pre-operative prophylaxis to prevent an IOP spike after eye surgery; give 1 drop in each eye once daily, beginning 3 days before surgery.

Loteprednol – synthetic steroid.  For control of most ocular inflammatory conditions, give 1 drop per eye 3 times daily.  Common side effects include increased intra-ocular pressure; monitor patient for increased IOP during treatment, and stop use if IOP spikes are noted.

Paracaine – combination mydriatic, cycloplegic and local anesthetic; used to anesthetize, dilate and paralyze the eye for examination.  For humans, give 1 drop per eye; maximum mydriatic effect occurs immediately, wears off in 1 hour.  For Vulcans and other species with a nictitating membrane (“second eyelid”), give 2 drops per eye; maximum effect occurs in 10 minutes, wears off in 45 minutes.

Phetetalin (ophthalmic) – macrolide antibiotic.  For infectious corneal ulcer or infectious keratitis, give 1 drop in the affected eye every 30 minutes round the clock until condition resolves.  For bacterial conjunctivitis, give 1 drop per eye four times daily for two weeks.  Do not use in patients with documented sensitivity to other macrolide antibiotics.

Retnax V – drug used to treat some cases of myopia by thinning the cornea.  This treatment method has fallen out of use due to poor predictability of results and high risk for complications, including keratitis, ectasia and corneal ulcer.  (Wavefront-enhanced corneal resculpting is the current standard of care.)  

Orthopedic:

Bicaridine – osteoregenerative medication, used to accelerate healing in bone fractures.  After setting and casting the injury, give 500 mg IM in 2 divided doses, twice daily for three weeks.  Bicaridine may be used in patients allergic to metorapan.

Metorapan – osteoregenerative medication; drug of choice for treating bone fractures.  After setting and casting the injury, give 200 mg IO (intraosseous injection) into the injured bone.  Do not use in patients with documented sensitivity to metorapan.  

Psychiatric/CNS:

Desegranine – psychiatric drug, used to aid in the memory recovery process in amnesiac patients.  Dosing varies by patient, but in general, give 5 mg IV by hypospray.
            N.B.  Desegranine is a Schedule IV drug; use with caution.

Lexorin – anti-vertigo agent.  To treat vertigo and disorientation, give 12.5 mg SC or IM every 24 hours.

Melorazine – see “Anesthetics and Sedatives,” above.  For acute psychiatric episodes (mania, schizophrenia, et al), give 20 mg IM by hypospray as an initial dose, then .15 mg/kg (approximately 10 mg in the “average” patient) every twelve hours thereafter.
            N.B.  Melorazine is a Schedule IV drug; use with caution.  

Peridaxon - esterase inhibitor, used to retard synaptic degradation in degenerative neurological disease.  For diagnosed conditions such as Forrester-Trent syndrome and irumodic syndrome, give 4 mg PO once daily; increase dose until symptoms are under control, up to 12 mg daily in divided doses.

Promethazine – anti-emetic drug, second line of treatment if vertazine cannot be used.  For motion sickness, nausea, vomiting and disorientation, give 50 mg PO or IM.  For “morning sickness” in pregnant patients, give 15 mg PO immediately upon waking, then every 3 hours thereafter.

Sertraline – a selective serotonin reuptake inhibitor, used as an antidepressant and mood stabilizer.  For control of major depressive and panic disorders including holodiction and HTSD, post-traumatic stress syndrome and other mood disorders, give 50 mg PO daily; dose may be increased as high as 100 mg. Use caution when combining sertraline with sedative medications.

Vertazine – anti-vertigo and anti-emetic drug.  For motion sickness, give 25 mg PO every 24 hours.  For general nausea and vomiting, give 15 mg every 12 hours.  Use caution in Trill patients, as vertazine can aggravate symptoms in cases of symbiont trauma.  

Reversal Agents:

Nalmefene – muscarinic agonist, used to reverse neuromuscular blockade.  Give 0.25 mcg/kg/hour IV, and monitor patient carefully.

Narcan – opioid antagonist, used to reverse the effects of most “recreational” drugs, also used as an antidote for opioid overdose.  Give 2 mg IV every 30 minutes until all drug is cleared, and monitor patient carefully.
            N.B.  Narcan will clear the bloodstream of all opioids, whether therapeutic or recreational.  Use caution when combining Narcan with opioid analgesics, as it will negate these drugs' pain-relieving effect.

Netinaline – CNS stimulant, used to reverse unconsciousness and some mild comas.  For unconsciousness without CNS complications, give 15 mg IV; increase dosing to 25 mg if necessary.  To reverse drug-induced coma, give 0.1 mg/kg/hour IV until patient is awake and alert.

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Original website is Copyright © 2001, Karen MorrisURL:
 http://www.angelfire.com/scifi/Dree/Medical_Database/Index.htm

Edited and expanded by Carol Thompson from Star Trek Encyclopedia and the following websites:
http://www.fsgsims.com/ussaurora/intro.htm and http://www.startrek.com

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